Common Misdiagnoses of CREST Syndrome

CREST syndrome is a type of systemic scleroderma associated with antibodies that go against centromeres (regions of DNA chromosomes), usually in the kidneys and lungs. The condition is progressive and chronic, is an autoimmune disease that attacks the body's connective tissues, and may affect any part of the body including the skin, muscles, blood vessels, digestive tract and other organs. The acronym represents the group of conditions usually associated with the syndrome. These five conditions are: calcinosis, Raynard's syndrome, esophageal dysmotility, sclerodactyly and telangiectasia. Even though these pathologies are the ones most associated with the syndrome, the list is not exclusive as more conditions are also associated with CREST syndrome.

Symptoms of CREST Syndrome

Symptoms of CREST syndrome vary depending on the pathology. For example, those with Raynaud's syndrome may experience paleness, coldness, numbness in the fingers and toes, as well as pain. Other symptoms related to CREST syndrome may include swelling of the face, hands, forearms, face, as well as the lower extremities. Generally, the skin around these areas hardens and thickens and movement becomes difficult. Additionally, muscles become weak and joint stiffness may set in.

Because of the generalized systemic nature of the syndrome, it may affect any organ in the body. Resulting symptoms may include chest pain, abnormal heart rhythms, kidney failure, seizures, hypertension and heart failure.

Diagnoses of CREST Syndrome

The diagnosis of CREST syndrome begins with a thorough medical history and a physical exam. This is usually followed with an anticentromere antibody blood test. This test provides a definite diagnosis as those with systemic scleroderma do not have high levels of of anticentromere antibodies. Additionally a biopsy may be ordered where a small portion of affected tissue is microscopically examined for excessive amounts of collagen.

Although there is no cure for CREST syndrome, the condition may be managed with early care and medications. Depending on the severity of the symptoms, certain medications may be prescribed such as vasodilators that open blood vessels in the finger and toes. This medication will also minimize the sensation of cold and numbness. Non-steroidal anti-inflammatory drugs may also be prescribed to control swelling, inflammation and pain.

Common Misdiagnoses of CREST Syndrome

CREST syndrome is often misdiagnosed or treatment delayed because of vague symptoms such as indigestion and swallowing difficulty. Conditions that CREST syndrome may be mistaken for are gastrointestinal disorders and rheumatoid arthritis.

Find a Lawyer

If you suffer from complications of CREST syndrome because it was not diagnosed timely or properly, you may have a cause of action for medical malpractice. You can get compensated for any medical cost and lost wages due to the malpractice. You may also receive damages for the unnecessary pain and suffering you had to go through because of the medical negligence. Find a lawyer to discuss your case.